Hearing loss and hair cell death in mice given the cholesterol-chelating agent hydroxypropyl-β-cyclo...
Hearing loss and hair cell death in mice given the cholesterol-chelating agent hydroxypropyl-β-cyclodextrin
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Cyclodextrins are sugar compounds that are increasingly finding medicinal uses due to their ability to complex with hydrophobic molecules. One cyclodextrin in particular, 2-hydroxypropyl-β-cyclodextrin (HPβCD), is used as a carrier to solubilize lipophilic drugs and is itself being considered as a therapeutic agent for treatment of Niemann-Pick Typ...
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Full title
Hearing loss and hair cell death in mice given the cholesterol-chelating agent hydroxypropyl-β-cyclodextrin
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TN_cdi_plos_journals_1327231911
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1327231911
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0053280