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Hearing loss and hair cell death in mice given the cholesterol-chelating agent hydroxypropyl-β-cyclo...

Hearing loss and hair cell death in mice given the cholesterol-chelating agent hydroxypropyl-β-cyclo...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1327231911

Hearing loss and hair cell death in mice given the cholesterol-chelating agent hydroxypropyl-β-cyclodextrin

About this item

Full title

Hearing loss and hair cell death in mice given the cholesterol-chelating agent hydroxypropyl-β-cyclodextrin

Publisher

United States: Public Library of Science

Journal title

PloS one, 2012-12, Vol.7 (12), p.e53280

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Cyclodextrins are sugar compounds that are increasingly finding medicinal uses due to their ability to complex with hydrophobic molecules. One cyclodextrin in particular, 2-hydroxypropyl-β-cyclodextrin (HPβCD), is used as a carrier to solubilize lipophilic drugs and is itself being considered as a therapeutic agent for treatment of Niemann-Pick Typ...

Alternative Titles

Full title

Hearing loss and hair cell death in mice given the cholesterol-chelating agent hydroxypropyl-β-cyclodextrin

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1327231911

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1327231911

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0053280

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