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Diclofenac Prolongs Repolarization in Ventricular Muscle with Impaired Repolarization Reserve

Diclofenac Prolongs Repolarization in Ventricular Muscle with Impaired Repolarization Reserve

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1327231946

Diclofenac Prolongs Repolarization in Ventricular Muscle with Impaired Repolarization Reserve

About this item

Full title

Diclofenac Prolongs Repolarization in Ventricular Muscle with Impaired Repolarization Reserve

Publisher

United States: Public Library of Science

Journal title

PloS one, 2012-12, Vol.7 (12), p.e53255-e53255

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The aim of the present work was to characterize the electrophysiological effects of the non-steroidal anti-inflammatory drug diclofenac and to study the possible proarrhythmic potency of the drug in ventricular muscle.
Ion currents were recorded using voltage clamp technique in canine single ventricular cells and action potentials were obtained...

Alternative Titles

Full title

Diclofenac Prolongs Repolarization in Ventricular Muscle with Impaired Repolarization Reserve

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1327231946

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1327231946

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0053255

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