In vivo targeting of ADAM9 gene expression using lentivirus-delivered shRNA suppresses prostate canc...
In vivo targeting of ADAM9 gene expression using lentivirus-delivered shRNA suppresses prostate cancer growth by regulating REG4 dependent cell cycle progression
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Cancer cells respond to stress by activating a variety of survival signaling pathways. A disintegrin and metalloproteinase (ADAM) 9 is upregulated during cancer progression and hormone therapy, functioning in part through an increase in reactive oxygen species. Here, we present in vitro and in vivo evidence that therapeutic targeting of ADAM9 gene...
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In vivo targeting of ADAM9 gene expression using lentivirus-delivered shRNA suppresses prostate cancer growth by regulating REG4 dependent cell cycle progression
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TN_cdi_plos_journals_1327256365
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1327256365
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1932-6203
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1932-6203
DOI
10.1371/journal.pone.0053795