Elevated Expression of the Integrin-Associated Protein PINCH Suppresses the Defects of Drosophila me...
Elevated Expression of the Integrin-Associated Protein PINCH Suppresses the Defects of Drosophila melanogaster Muscle Hypercontraction Mutants
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United States: Public Library of Science
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English
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United States: Public Library of Science
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A variety of human diseases arise from mutations that alter muscle contraction. Evolutionary conservation allows genetic studies in Drosophila melanogaster to be used to better understand these myopathies and suggest novel therapeutic strategies. Integrin-mediated adhesion is required to support muscle structure and function, and expression of Inte...
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Full title
Elevated Expression of the Integrin-Associated Protein PINCH Suppresses the Defects of Drosophila melanogaster Muscle Hypercontraction Mutants
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TN_cdi_plos_journals_1327764175
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1327764175
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1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1003406
