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Characterization of the Distal Promoter of the Human Pyruvate Carboxylase Gene in Pancreatic Beta Ce...

Characterization of the Distal Promoter of the Human Pyruvate Carboxylase Gene in Pancreatic Beta Ce...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1327979183

Characterization of the Distal Promoter of the Human Pyruvate Carboxylase Gene in Pancreatic Beta Cells

About this item

Full title

Characterization of the Distal Promoter of the Human Pyruvate Carboxylase Gene in Pancreatic Beta Cells

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-01, Vol.8 (1), p.e55139-e55139

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Pyruvate carboxylase (PC) is an enzyme that plays a crucial role in many biosynthetic pathways in various tissues including glucose-stimulated insulin secretion. In the present study, we identify promoter usage of the human PC gene in pancreatic beta cells. The data show that in the human, two alternative promoters, proximal and distal, are respons...

Alternative Titles

Full title

Characterization of the Distal Promoter of the Human Pyruvate Carboxylase Gene in Pancreatic Beta Cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1327979183

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1327979183

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0055139

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