Measuring airway surface liquid depth in ex vivo mouse airways by x-ray imaging for the assessment o...
Measuring airway surface liquid depth in ex vivo mouse airways by x-ray imaging for the assessment of cystic fibrosis airway therapies
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
In the airways of those with cystic fibrosis (CF), the leading pathophysiological hypothesis is that an ion channel defect results in a relative decrease in airway surface liquid (ASL) volume, producing thick and sticky mucus that facilitates the establishment and progression of early fatal lung disease. This hypothesis predicts that any successful...
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Full title
Measuring airway surface liquid depth in ex vivo mouse airways by x-ray imaging for the assessment of cystic fibrosis airway therapies
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TN_cdi_plos_journals_1328020933
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1328020933
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0055822
