Silencing mutated β-catenin inhibits cell proliferation and stimulates apoptosis in the adrenocortic...
Silencing mutated β-catenin inhibits cell proliferation and stimulates apoptosis in the adrenocortical cancer cell line H295R
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Adrenocortical carcinoma (ACC) is a rare and highly aggressive endocrine neoplasm, with limited therapeutic options. Activating β-catenin somatic mutations are found in ACC and have been associated with a poor clinical outcome. In fact, activation of the Wnt/β-catenin signaling pathway seems to play a major role in ACC aggressiveness, and might, th...
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Full title
Silencing mutated β-catenin inhibits cell proliferation and stimulates apoptosis in the adrenocortical cancer cell line H295R
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TN_cdi_plos_journals_1330877216
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1330877216
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0055743
