EspO1-2 regulates EspM2-mediated RhoA activity to stabilize formation of focal adhesions in enterohe...
EspO1-2 regulates EspM2-mediated RhoA activity to stabilize formation of focal adhesions in enterohemorrhagic Escherichia coli-infected host cells
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Enterohemorrhagic Escherichia coli (EHEC) Sakai strain encodes two homologous type III effectors, EspO1-1 and EspO1-2. These EspO1s have amino acid sequence homology with Shigella OspE, which targets integrin-linked kinase to stabilize formation of focal adhesions (FAs). Like OspE, EspO1-1 was localized to FAs in EHEC-infected cells, but EspO1-2 wa...
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Full title
EspO1-2 regulates EspM2-mediated RhoA activity to stabilize formation of focal adhesions in enterohemorrhagic Escherichia coli-infected host cells
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TN_cdi_plos_journals_1330877566
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1330877566
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0055960
