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Membrane Phospholipid Augments Cytochrome P4501a Enzymatic Activity by Modulating Structural Conform...

Membrane Phospholipid Augments Cytochrome P4501a Enzymatic Activity by Modulating Structural Conform...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1330881080

Membrane Phospholipid Augments Cytochrome P4501a Enzymatic Activity by Modulating Structural Conformation during Detoxification of Xenobiotics

About this item

Full title

Membrane Phospholipid Augments Cytochrome P4501a Enzymatic Activity by Modulating Structural Conformation during Detoxification of Xenobiotics

Author / Creator

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-02, Vol.8 (2), p.e57919

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Cytochrome P450 is a superfamily of membrane-bound hemoprotein that gets involved with the degradation of xenobiotics and internal metabolites. Accumulated body of evidence indicates that phospholipids play a crucial role in determining the enzymatic activity of cytochrome P450 in the microenvironment by modulating its structure during detoxificati...

Alternative Titles

Full title

Membrane Phospholipid Augments Cytochrome P4501a Enzymatic Activity by Modulating Structural Conformation during Detoxification of Xenobiotics

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1330881080

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1330881080

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0057919

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