Vitamin K-antagonists accelerate atherosclerotic calcification and induce a vulnerable plaque phenot...
Vitamin K-antagonists accelerate atherosclerotic calcification and induce a vulnerable plaque phenotype
About this item
Full title
Author / Creator
Schurgers, Leon J , Joosen, Ivo A , Laufer, Eduard M , Chatrou, Martijn L L , Herfs, Marjolein , Winkens, Mark H M , Westenfeld, Ralf , Veulemans, Verena , Krueger, Thilo , Shanahan, Catherine M , Jahnen-Dechent, Willi , Biessen, Erik , Narula, Jagat , Vermeer, Cees , Hofstra, Leonard and Reutelingsperger, Chris P
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
Vitamin K-antagonists (VKA) are treatment of choice and standard care for patients with venous thrombosis and thromboembolic risk. In experimental animal models as well as humans, VKA have been shown to promote medial elastocalcinosis. As vascular calcification is considered an independent risk factor for plaque instability, we here investigated th...
Alternative Titles
Full title
Vitamin K-antagonists accelerate atherosclerotic calcification and induce a vulnerable plaque phenotype
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1330881851
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1330881851
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0043229
