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mRNA expression levels in failing human hearts predict cellular electrophysiological remodeling: a p...

mRNA expression levels in failing human hearts predict cellular electrophysiological remodeling: a p...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1330881980

mRNA expression levels in failing human hearts predict cellular electrophysiological remodeling: a population-based simulation study

About this item

Full title

mRNA expression levels in failing human hearts predict cellular electrophysiological remodeling: a population-based simulation study

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-02, Vol.8 (2), p.e56359-e56359

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Differences in mRNA expression levels have been observed in failing versus non-failing human hearts for several membrane channel proteins and accessory subunits. These differences may play a causal role in electrophysiological changes observed in human heart failure and atrial fibrillation, such as action potential (AP) prolongation, increased AP t...

Alternative Titles

Full title

mRNA expression levels in failing human hearts predict cellular electrophysiological remodeling: a population-based simulation study

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1330881980

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1330881980

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0056359

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