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IL-23 Dependent and Independent Stages of Experimental Arthritis: No Clinical Effect of Therapeutic...

IL-23 Dependent and Independent Stages of Experimental Arthritis: No Clinical Effect of Therapeutic...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1330882643

IL-23 Dependent and Independent Stages of Experimental Arthritis: No Clinical Effect of Therapeutic IL-23p19 Inhibition in Collagen-induced Arthritis

About this item

Full title

IL-23 Dependent and Independent Stages of Experimental Arthritis: No Clinical Effect of Therapeutic IL-23p19 Inhibition in Collagen-induced Arthritis

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-02, Vol.8 (2), p.e57553

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

IL-23p19 deficient mice have revealed a critical role of IL-23 in the development of experimental autoimmune diseases, such as collagen-induced arthritis (CIA). Neutralizing IL-23 after onset of CIA in rats has been shown to reduce paw volume, but the effect on synovial inflammation and the immunological autoimmune response is not clear. In this st...

Alternative Titles

Full title

IL-23 Dependent and Independent Stages of Experimental Arthritis: No Clinical Effect of Therapeutic IL-23p19 Inhibition in Collagen-induced Arthritis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1330882643

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1330882643

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0057553

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