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Chemerin Is an Antimicrobial Agent in Human Epidermis

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Chemerin Is an Antimicrobial Agent in Human Epidermis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1330889373

Chemerin Is an Antimicrobial Agent in Human Epidermis

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United States: Public Library of Science

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Contents

Chemerin, a chemoattractant ligand for chemokine-like receptor 1 (CMKLR1) is predicted to share similar tertiary structure with antibacterial cathelicidins. Recombinant chemerin has antimicrobial activity. Here we show that endogenous chemerin is abundant in human epidermis, and that inhibition of bacteria growth by exudates from organ cultures of...

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Chemerin Is an Antimicrobial Agent in Human Epidermis

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Record Identifier

TN_cdi_plos_journals_1330889373

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1330889373

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ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0058709

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