Derivation and expansion using only small molecules of human neural progenitors for neurodegenerativ...
Derivation and expansion using only small molecules of human neural progenitors for neurodegenerative disease modeling
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Author / Creator
Reinhardt, Peter , Glatza, Michael , Hemmer, Kathrin , Tsytsyura, Yaroslav , Thiel, Cora S , Höing, Susanne , Moritz, Sören , Parga, Juan A , Wagner, Lydia , Bruder, Jan M , Wu, Guangming , Schmid, Benjamin , Röpke, Albrecht , Klingauf, Jürgen , Schwamborn, Jens C , Gasser, Thomas , Schöler, Hans R and Sterneckert, Jared
Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Phenotypic drug discovery requires billions of cells for high-throughput screening (HTS) campaigns. Because up to several million different small molecules will be tested in a single HTS campaign, even small variability within the cell populations for screening could easily invalidate an entire campaign. Neurodegenerative assays are particularly ch...
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Full title
Derivation and expansion using only small molecules of human neural progenitors for neurodegenerative disease modeling
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TN_cdi_plos_journals_1330891353
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1330891353
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0059252
