NADH Oxidase Functions as an Adhesin in Streptococcus pneumoniae and Elicits a Protective Immune Res...
NADH Oxidase Functions as an Adhesin in Streptococcus pneumoniae and Elicits a Protective Immune Response in Mice
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Muchnik, Lena , Adawi, Asad , Ohayon, Ariel , Dotan, Shahar , Malka, Itai , Azriel, Shalhevet , Shagan, Marilou , Portnoi, Maxim , Kafka, Daniel , Nahmani, Hannie , Porgador, Angel , Gershoni, Johnatan M. , Morrison, Donald A. , Mitchell, Andrea , Tal, Michael , Ellis, Ronald , Dagan, Ron and Nebenzahl, Yaffa Mizrachi
Publisher
United States: Public Library of Science
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English
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Publisher
United States: Public Library of Science
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Contents
The initial event in disease caused by S. pneumoniae is adhesion of the bacterium to respiratory epithelial cells, mediated by surface expressed molecules including cell-wall proteins. NADH oxidase (NOX), which reduces free oxygen to water in the cytoplasm, was identified in a non-lectin enriched pneumococcal cell-wall fraction. Recombinant NOX (rN...
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Full title
NADH Oxidase Functions as an Adhesin in Streptococcus pneumoniae and Elicits a Protective Immune Response in Mice
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TN_cdi_plos_journals_1330893564
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1330893564
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0061128