Molecules Altering the Intracellular Thiol Content Modulate NF-kB and STAT-1/IRF-1 Signalling Pathwa...
Molecules Altering the Intracellular Thiol Content Modulate NF-kB and STAT-1/IRF-1 Signalling Pathways and IL-12 p40 and IL-27 p28 Production in Murine Macrophages
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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The aim of this study was to investigate the molecular mechanisms involved in the production of Th1 cytokines, namely IL-12 and IL-27, when the intra-macrophage redox state was altered by different chemical entities such as GSH-C4, which is reduced glutathione carrying an aliphatic chain, or I-152, a pro-drug of N-acetyl-cysteine (NAC) and beta-mer...
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Full title
Molecules Altering the Intracellular Thiol Content Modulate NF-kB and STAT-1/IRF-1 Signalling Pathways and IL-12 p40 and IL-27 p28 Production in Murine Macrophages
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TN_cdi_plos_journals_1330895089
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1330895089
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0057866
