Minocycline Suppresses Interleukine-6, Its Receptor System and Signaling Pathways and Impairs Migrat...
Minocycline Suppresses Interleukine-6, Its Receptor System and Signaling Pathways and Impairs Migration, Invasion and Adhesion Capacity of Ovarian Cancer Cells: In Vitro and In Vivo Studies
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Interleukin (IL)-6 has been shown to be a major contributing factor in growth and progression of ovarian cancer. The cytokine exerts pro-tumorigenic activity through activation of several signaling pathways in particular signal transducer and activator of transcription (STAT3) and extracellular signal-regulated kinase (ERK)1/2. Hence, targeting IL-...
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Minocycline Suppresses Interleukine-6, Its Receptor System and Signaling Pathways and Impairs Migration, Invasion and Adhesion Capacity of Ovarian Cancer Cells: In Vitro and In Vivo Studies
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TN_cdi_plos_journals_1330895275
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1330895275
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0060817
