Zebrafish hoxd4a Acts Upstream of meis1.1 to Direct Vasculogenesis, Angiogenesis and Hematopoiesis
Zebrafish hoxd4a Acts Upstream of meis1.1 to Direct Vasculogenesis, Angiogenesis and Hematopoiesis
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Mice lacking the 4th-group paralog Hoxd4 display malformations of the anterior vertebral column, but are viable and fertile. Here, we report that zebrafish embryos having decreased function of the orthologous hoxd4a gene manifest striking perturbations in vasculogenesis, angiogenesis and primitive and definitive hematopoiesis. These defects are pre...
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Full title
Zebrafish hoxd4a Acts Upstream of meis1.1 to Direct Vasculogenesis, Angiogenesis and Hematopoiesis
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TN_cdi_plos_journals_1330898413
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1330898413
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0058857