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Rab GTPases regulate endothelial cell protein C receptor-mediated endocytosis and trafficking of fac...

Rab GTPases regulate endothelial cell protein C receptor-mediated endocytosis and trafficking of fac...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1330898828

Rab GTPases regulate endothelial cell protein C receptor-mediated endocytosis and trafficking of factor VIIa

About this item

Full title

Rab GTPases regulate endothelial cell protein C receptor-mediated endocytosis and trafficking of factor VIIa

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-03, Vol.8 (3), p.e59304-e59304

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Recent studies have established that factor VIIa (FVIIa) binds to the endothelial cell protein C receptor (EPCR). FVIIa binding to EPCR may promote the endocytosis of this receptor/ligand complex. Rab GTPases are known to play a crucial role in the endocytic and exocytic pathways of receptors or receptor/ligand complexes. The present study was unde...

Alternative Titles

Full title

Rab GTPases regulate endothelial cell protein C receptor-mediated endocytosis and trafficking of factor VIIa

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1330898828

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1330898828

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0059304

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