Novel DNA Variants and Mutation Frequencies of hMLH1 and hMSH2 Genes in Colorectal Cancer in the Nor...
Novel DNA Variants and Mutation Frequencies of hMLH1 and hMSH2 Genes in Colorectal Cancer in the Northeast China Population
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Author / Creator
Hu, Fulan , Li, Dandan , Wang, Yibaina , Yao, Xiaoping , Zhang, Wencui , Liang, Jing , Lin, Chunqing , Ren, Jiaojiao , Zhu, Lin , Wu, Zhiwei , Li, Shuying , Li, Ye , Zhao, Xiaojuan , Cui, Binbin , Dong, Xinshu , Tian, Suli and Zhao, Yashuang
Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Research on hMLH1 and hMSH2 mutations tend to focus on Lynch syndrome (LS) and LS-like colorectal cancer (CRC). No studies to date have assessed the role of hMLH1 and hMSH2 genes in mass sporadic CRC (without preselection by MSI or early age of onset). We aimed to identify novel hMLH1 and hMSH2 DNA variants, to determine the mutation frequencies an...
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Full title
Novel DNA Variants and Mutation Frequencies of hMLH1 and hMSH2 Genes in Colorectal Cancer in the Northeast China Population
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TN_cdi_plos_journals_1330914068
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1330914068
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0060233
