Endocardial to Myocardial Notch-Wnt-Bmp Axis Regulates Early Heart Valve Development
Endocardial to Myocardial Notch-Wnt-Bmp Axis Regulates Early Heart Valve Development
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Endocardial to mesenchymal transformation (EMT) is a fundamental cellular process required for heart valve formation. Notch, Wnt and Bmp pathways are known to regulate this process. To further address how these pathways coordinate in the process, we specifically disrupted Notch1 or Jagged1 in the endocardium of mouse embryonic hearts and showed tha...
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Full title
Endocardial to Myocardial Notch-Wnt-Bmp Axis Regulates Early Heart Valve Development
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TN_cdi_plos_journals_1330914074
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1330914074
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0060244
