Pro-Asthmatic Cytokines Regulate Unliganded and Ligand-Dependent Glucocorticoid Receptor Signaling i...
Pro-Asthmatic Cytokines Regulate Unliganded and Ligand-Dependent Glucocorticoid Receptor Signaling in Airway Smooth Muscle
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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To elucidate the regulation of glucocorticoid receptor (GR) signaling under pro-asthmatic conditions, cultured human airway smooth muscle (HASM) cells were treated with proinflammatory cytokines or GR ligands alone and in combination, and then examined for induced changes in ligand-dependent and -independent GR activation and downstream signaling e...
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Pro-Asthmatic Cytokines Regulate Unliganded and Ligand-Dependent Glucocorticoid Receptor Signaling in Airway Smooth Muscle
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TN_cdi_plos_journals_1330914171
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1330914171
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0060452
