mTOR-Controlled Autophagy Requires Intracellular Ca2+ Signaling
mTOR-Controlled Autophagy Requires Intracellular Ca2+ Signaling
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Publisher
San Francisco: Public Library of Science
Journal title
Language
English
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Publisher
San Francisco: Public Library of Science
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Scope and Contents
Contents
Autophagy is a lysosomal degradation pathway important for cellular homeostasis and survival. Inhibition of the mammalian target of rapamycin (mTOR) is the best known trigger for autophagy stimulation. In addition, intracellular Ca2+ regulates autophagy, but its exact role remains ambiguous. Here, we report that the mTOR inhibitor rapamycin, while...
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Full title
mTOR-Controlled Autophagy Requires Intracellular Ca2+ Signaling
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TN_cdi_plos_journals_1330914715
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1330914715
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0061020
