Mesenchymal Transition and PDGFRA Amplification/Mutation Are Key Distinct Oncogenic Events in Pediat...
Mesenchymal Transition and PDGFRA Amplification/Mutation Are Key Distinct Oncogenic Events in Pediatric Diffuse Intrinsic Pontine Gliomas
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Author / Creator
Puget, Stephanie , Philippe, Cathy , Bax, Dorine A. , Job, Bastien , Varlet, Pascale , Junier, Marie-Pierre , Andreiuolo, Felipe , Carvalho, Dina , Reis, Ricardo , Guerrini-Rousseau, Lea , Roujeau, Thomas , Dessen, Philippe , Richon, Catherine , Lazar, Vladimir , Le Teuff, Gwenael , Sainte-Rose, Christian , Geoerger, Birgit , Vassal, Gilles , Jones, Chris and Grill, Jacques
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publication information
Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Diffuse intrinsic pontine glioma (DIPG) is one of the most frequent malignant pediatric brain tumor and its prognosis is universaly fatal. No significant improvement has been made in last thirty years over the standard treatment with radiotherapy. To address the paucity of understanding of DIPGs, we have carried out integrated molecular profiling o...
Alternative Titles
Full title
Mesenchymal Transition and PDGFRA Amplification/Mutation Are Key Distinct Oncogenic Events in Pediatric Diffuse Intrinsic Pontine Gliomas
Authors, Artists and Contributors
Author / Creator
Philippe, Cathy
Bax, Dorine A.
Job, Bastien
Varlet, Pascale
Junier, Marie-Pierre
Andreiuolo, Felipe
Carvalho, Dina
Reis, Ricardo
Guerrini-Rousseau, Lea
Roujeau, Thomas
Dessen, Philippe
Richon, Catherine
Lazar, Vladimir
Le Teuff, Gwenael
Sainte-Rose, Christian
Geoerger, Birgit
Vassal, Gilles
Jones, Chris
Grill, Jacques
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1332824833
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1332824833
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0030313