Differential macrophage activation alters the expression profile of NTPDase and ecto-5'-nucleotidase
Differential macrophage activation alters the expression profile of NTPDase and ecto-5'-nucleotidase
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Author / Creator
Zanin, Rafael Fernandes , Braganhol, Elizandra , Bergamin, Letícia Scussel , Campesato, Luís Felipe Ingrassia , Filho, Alfeu Zanotto , Moreira, José Cláudio Fonseca , Morrone, Fernanda Bueno , Sévigny, Jean , Schetinger, Maria Rosa Chitolina , de Souza Wyse, Angela Terezinha and Battastini, Ana Maria Oliveira
Publisher
United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Macrophages are key elements in the inflammatory process, whereas depending on the micro-environmental stimulation they exhibit a pro-inflammatory (classical/M1) or an anti-inflammatory/reparatory (alternative/M2) phenotype. Extracellular ATP can act as a danger signal whereas adenosine generally serves as a negative feedback mechanism to limit inf...
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Full title
Differential macrophage activation alters the expression profile of NTPDase and ecto-5'-nucleotidase
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TN_cdi_plos_journals_1332949797
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1332949797
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0031205
