Expression levels of the ABCG2 multidrug transporter in human erythrocytes correspond to pharmacolog...
Expression levels of the ABCG2 multidrug transporter in human erythrocytes correspond to pharmacologically relevant genetic variations
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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We have developed a rapid, simple and reliable, antibody-based flow cytometry assay for the quantitative determination of membrane proteins in human erythrocytes. Our method reveals significant differences between the expression levels of the wild-type ABCG2 protein and the heterozygous Q141K polymorphic variant. Moreover, we find that nonsense mut...
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Full title
Expression levels of the ABCG2 multidrug transporter in human erythrocytes correspond to pharmacologically relevant genetic variations
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TN_cdi_plos_journals_1335101554
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1335101554
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0048423
