HIV-1 Tat Promotes Integrin-Mediated HIV Transmission to Dendritic Cells by Binding Env Spikes and C...
HIV-1 Tat Promotes Integrin-Mediated HIV Transmission to Dendritic Cells by Binding Env Spikes and Competes Neutralization by Anti-HIV Antibodies
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Full title
Author / Creator
Monini, Paolo , Cafaro, Aurelio , Srivastava, Indresh K. , Moretti, Sonia , Sharma, Victoria A. , Andreini, Claudia , Chiozzini, Chiara , Ferrantelli, Flavia , Cossut, Maria R. Pavone , Tripiciano, Antonella , Nappi, Filomena , Longo, Olimpia , Bellino, Stefania , Picconi, Orietta , Fanales-Belasio, Emanuele , Borsetti, Alessandra , Toschi, Elena , Schiavoni, Ilaria , Bacigalupo, Ilaria , Kan, Elaine , Sernicola, Leonardo , Maggiorella, Maria T. , Montin, Katy , Porcu, Marco , Leone, Patrizia , Leone, Pasqualina , Collacchi, Barbara , Palladino, Clelia , Ridolfi, Barbara , Falchi, Mario , Macchia, Iole , Ulmer, Jeffrey B. , Buttò, Stefano , Sgadari, Cecilia , Magnani, Mauro , Federico, Maurizio P. M. , Titti, Fausto , Banci, Lucia , Dallocchio, Franco , Rappuoli, Rino , Ensoli, Fabrizio , Barnett, Susan W. , Garaci, Enrico and Ensoli, Barbara
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
Use of Env in HIV vaccine development has been disappointing. Here we show that, in the presence of a biologically active Tat subunit vaccine, a trimeric Env protein prevents in monkeys virus spread from the portal of entry to regional lymph nodes. This appears to be due to specific interactions between Tat and Env spikes that form a novel virus en...
Alternative Titles
Full title
HIV-1 Tat Promotes Integrin-Mediated HIV Transmission to Dendritic Cells by Binding Env Spikes and Competes Neutralization by Anti-HIV Antibodies
Authors, Artists and Contributors
Author / Creator
Cafaro, Aurelio
Srivastava, Indresh K.
Moretti, Sonia
Sharma, Victoria A.
Andreini, Claudia
Chiozzini, Chiara
Ferrantelli, Flavia
Cossut, Maria R. Pavone
Tripiciano, Antonella
Nappi, Filomena
Longo, Olimpia
Bellino, Stefania
Picconi, Orietta
Fanales-Belasio, Emanuele
Borsetti, Alessandra
Toschi, Elena
Schiavoni, Ilaria
Bacigalupo, Ilaria
Kan, Elaine
Sernicola, Leonardo
Maggiorella, Maria T.
Montin, Katy
Porcu, Marco
Leone, Patrizia
Leone, Pasqualina
Collacchi, Barbara
Palladino, Clelia
Ridolfi, Barbara
Falchi, Mario
Macchia, Iole
Ulmer, Jeffrey B.
Buttò, Stefano
Sgadari, Cecilia
Magnani, Mauro
Federico, Maurizio P. M.
Titti, Fausto
Banci, Lucia
Dallocchio, Franco
Rappuoli, Rino
Ensoli, Fabrizio
Barnett, Susan W.
Garaci, Enrico
Ensoli, Barbara
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1335102027
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1335102027
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0048781
