Characterization of a FGF19 variant with altered receptor specificity revealed a central role for FG...
Characterization of a FGF19 variant with altered receptor specificity revealed a central role for FGFR1c in the regulation of glucose metabolism
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Diabetes and associated metabolic conditions have reached pandemic proportions worldwide, and there is a clear unmet medical need for new therapies that are both effective and safe. FGF19 and FGF21 are distinctive members of the FGF family that function as endocrine hormones. Both have potent effects on normalizing glucose, lipid, and energy homeos...
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Full title
Characterization of a FGF19 variant with altered receptor specificity revealed a central role for FGFR1c in the regulation of glucose metabolism
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TN_cdi_plos_journals_1338842385
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1338842385
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0033603
