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FOXM1 Induces a Global Methylation Signature That Mimics the Cancer Epigenome in Head and Neck Squam...

FOXM1 Induces a Global Methylation Signature That Mimics the Cancer Epigenome in Head and Neck Squam...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1338842974

FOXM1 Induces a Global Methylation Signature That Mimics the Cancer Epigenome in Head and Neck Squamous Cell Carcinoma

About this item

Full title

FOXM1 Induces a Global Methylation Signature That Mimics the Cancer Epigenome in Head and Neck Squamous Cell Carcinoma

Publisher

United States: Public Library of Science

Journal title

PloS one, 2012-03, Vol.7 (3), p.e34329-e34329

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The oncogene FOXM1 has been implicated in all major types of human cancer. We recently showed that aberrant FOXM1 expression causes stem cell compartment expansion resulting in the initiation of hyperplasia. We have previously shown that FOXM1 regulates HELLS, a SNF2/helicase involved in DNA methylation, implicating FOXM1 in epigenetic regulation....

Alternative Titles

Full title

FOXM1 Induces a Global Methylation Signature That Mimics the Cancer Epigenome in Head and Neck Squamous Cell Carcinoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1338842974

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1338842974

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0034329

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