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Cardiac Protection by Preconditioning Is Generated via an Iron-Signal Created by Proteasomal Degrada...

Cardiac Protection by Preconditioning Is Generated via an Iron-Signal Created by Proteasomal Degrada...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1339095903

Cardiac Protection by Preconditioning Is Generated via an Iron-Signal Created by Proteasomal Degradation of Iron Proteins

About this item

Full title

Cardiac Protection by Preconditioning Is Generated via an Iron-Signal Created by Proteasomal Degradation of Iron Proteins

Publisher

United States: Public Library of Science

Journal title

PloS one, 2012-11, Vol.7 (11), p.e48947-e48947

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Ischemia associated injury of the myocardium is caused by oxidative damage during reperfusion. Myocardial protection by ischemic preconditioning (IPC) was shown to be mediated by a transient 'iron-signal' that leads to the accumulation of apoferritin and sequestration of reactive iron released during the ischemia. Here we identified the source of t...

Alternative Titles

Full title

Cardiac Protection by Preconditioning Is Generated via an Iron-Signal Created by Proteasomal Degradation of Iron Proteins

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1339095903

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1339095903

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0048947

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