IFN regulatory factor 8 is a key constitutive determinant of the morphological and molecular propert...
IFN regulatory factor 8 is a key constitutive determinant of the morphological and molecular properties of microglia in the CNS
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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IFN regulatory factor (IRF) 8 is a transcription factor that has a key role in the cellular response to IFN-γ and is pivotal in myeloid cell differentiation. Whether IRF8 plays a role in the development and function of microglia, the tissue-resident myeloid cells of the brain, is unknown. Here, we show IRF8 is a constitutively produced nuclear fact...
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IFN regulatory factor 8 is a key constitutive determinant of the morphological and molecular properties of microglia in the CNS
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TN_cdi_plos_journals_1339168636
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1339168636
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0049851
