Long-term inhibition of xanthine oxidase by febuxostat does not decrease blood pressure in deoxycort...
Long-term inhibition of xanthine oxidase by febuxostat does not decrease blood pressure in deoxycorticosterone acetate (DOCA)-salt hypertensive rats
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Xanthine oxidase and its products, uric acid and ROS, have been implicated in the pathogenesis of cardiovascular disease, such as hypertension. We have previously reported that allopurinol inhibition of XO does not alter the progression of deoxycorticosterone acetate (DOCA)-salt hypertension in rats. However other researchers have observed a reduct...
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Long-term inhibition of xanthine oxidase by febuxostat does not decrease blood pressure in deoxycorticosterone acetate (DOCA)-salt hypertensive rats
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TN_cdi_plos_journals_1340279168
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1340279168
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1932-6203
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1932-6203
DOI
10.1371/journal.pone.0056046
