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Dual Action of BPC194: A Membrane Active Peptide Killing Bacterial Cells

Dual Action of BPC194: A Membrane Active Peptide Killing Bacterial Cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1343757285

Dual Action of BPC194: A Membrane Active Peptide Killing Bacterial Cells

About this item

Full title

Dual Action of BPC194: A Membrane Active Peptide Killing Bacterial Cells

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-04, Vol.8 (4), p.e61541-e61541

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Membrane active peptides can perturb the lipid bilayer in several ways, such as poration and fusion of the target cell membrane, and thereby efficiently kill bacterial cells. We probe here the mechanistic basis of membrane poration and fusion caused by membrane-active, antimicrobial peptides. We show that the cyclic antimicrobial peptide, BPC194, i...

Alternative Titles

Full title

Dual Action of BPC194: A Membrane Active Peptide Killing Bacterial Cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1343757285

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1343757285

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0061541

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