Treatment with activated protein C (aPC) is protective during the development of myocardial fibrosis...
Treatment with activated protein C (aPC) is protective during the development of myocardial fibrosis: an angiotensin II infusion model in mice
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Myocardial fibrosis contributes to the development of heart failure. Activated Protein C (aPC) is a circulating anticoagulant with anti-inflammatory and cytoprotective properties. Using a model of myocardial fibrosis second to Angiotensin II (AngII) infusion, we investigated the novel therapeutic function aPC in the development of fibrosis.
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Full title
Treatment with activated protein C (aPC) is protective during the development of myocardial fibrosis: an angiotensin II infusion model in mice
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TN_cdi_plos_journals_1344575947
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1344575947
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0045663
