Myeloid suppressor cell depletion augments antitumor activity in lung cancer
Myeloid suppressor cell depletion augments antitumor activity in lung cancer
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Myeloid derived suppressor cells (MDSC) are important regulators of immune responses. We evaluated the mechanistic role of MDSC depletion on antigen presenting cell (APC), NK, T cell activities and therapeutic vaccination responses in murine models of lung cancer.
Individual antibody mediated depletion of MDSC (anti-Gr1 or anti-Ly6G) enhanced th...
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Full title
Myeloid suppressor cell depletion augments antitumor activity in lung cancer
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TN_cdi_plos_journals_1348115227
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1348115227
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0040677
