Constructing endophenotypes of complex diseases using non-negative matrix factorization and adjusted...
Constructing endophenotypes of complex diseases using non-negative matrix factorization and adjusted rand index
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Complex diseases are typically caused by combinations of molecular disturbances that vary widely among different patients. Endophenotypes, a combination of genetic factors associated with a disease, offer a simplified approach to dissect complex trait by reducing genetic heterogeneity. Because molecular dissimilarities often exist between patients...
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Full title
Constructing endophenotypes of complex diseases using non-negative matrix factorization and adjusted rand index
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Record Identifier
TN_cdi_plos_journals_1348121942
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1348121942
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0040996
