Constitutively Active Androgen Receptor Variants Upregulate Expression of Mesenchymal Markers in Pro...
Constitutively Active Androgen Receptor Variants Upregulate Expression of Mesenchymal Markers in Prostate Cancer Cells
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Androgen receptor (AR) signaling pathway remains the foremost target of novel therapeutics for castration-resistant prostate cancer (CRPC). However, the expression of constitutively active AR variants lacking the carboxy-terminal region in CRPC may lead to therapy inefficacy. These AR variants are supposed to support PCa cell growth in an androgen-...
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Constitutively Active Androgen Receptor Variants Upregulate Expression of Mesenchymal Markers in Prostate Cancer Cells
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TN_cdi_plos_journals_1348130330
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1348130330
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1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0063466