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Constitutively Active Androgen Receptor Variants Upregulate Expression of Mesenchymal Markers in Pro...

Constitutively Active Androgen Receptor Variants Upregulate Expression of Mesenchymal Markers in Pro...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1348130330

Constitutively Active Androgen Receptor Variants Upregulate Expression of Mesenchymal Markers in Prostate Cancer Cells

About this item

Full title

Constitutively Active Androgen Receptor Variants Upregulate Expression of Mesenchymal Markers in Prostate Cancer Cells

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-05, Vol.8 (5), p.e63466-e63466

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Androgen receptor (AR) signaling pathway remains the foremost target of novel therapeutics for castration-resistant prostate cancer (CRPC). However, the expression of constitutively active AR variants lacking the carboxy-terminal region in CRPC may lead to therapy inefficacy. These AR variants are supposed to support PCa cell growth in an androgen-...

Alternative Titles

Full title

Constitutively Active Androgen Receptor Variants Upregulate Expression of Mesenchymal Markers in Prostate Cancer Cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1348130330

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1348130330

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0063466

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