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A lympho-follicular microenvironment is required for pathological prion protein deposition in chroni...

A lympho-follicular microenvironment is required for pathological prion protein deposition in chroni...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1350377128

A lympho-follicular microenvironment is required for pathological prion protein deposition in chronically inflamed tissues from scrapie-affected sheep

About this item

Full title

A lympho-follicular microenvironment is required for pathological prion protein deposition in chronically inflamed tissues from scrapie-affected sheep

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-05, Vol.8 (5), p.e62830-e62830

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

In sheep scrapie, pathological prion protein (PrP(Sc)) deposition occurs in the lymphoreticular and central nervous systems. We investigated PrP(Sc) distribution in scrapie-affected sheep showing simultaneous evidence of chronic lymphofollicular, lymphoproliferative/non-lymphofollicular, and/or granulomatous inflammations in their mammary gland, lu...

Alternative Titles

Full title

A lympho-follicular microenvironment is required for pathological prion protein deposition in chronically inflamed tissues from scrapie-affected sheep

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1350377128

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1350377128

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0062830

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