Acute Phase CD8+ T Lymphocytes against Alternate Reading Frame Epitopes Select for Rapid Viral Escap...
Acute Phase CD8+ T Lymphocytes against Alternate Reading Frame Epitopes Select for Rapid Viral Escape during SIV Infection
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
CD8+ T Lymphocytes (CTL) can control AIDS virus replication. However, natural selection favoring viral variants that escape CTL recognition is a common feature of both simian immunodeficiency virus (SIV) infection of macaques and HIV infection of humans. Emerging data indicate that CTL directed against alternate reading frame (ARF)-derived epitopes...
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Full title
Acute Phase CD8+ T Lymphocytes against Alternate Reading Frame Epitopes Select for Rapid Viral Escape during SIV Infection
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TN_cdi_plos_journals_1350377283
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1350377283
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0061383
