Integrated Metagenomics/Metaproteomics Reveals Human Host-Microbiota Signatures of Crohn's Disease
Integrated Metagenomics/Metaproteomics Reveals Human Host-Microbiota Signatures of Crohn's Disease
About this item
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Author / Creator
Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States) , Erickson, Alison R. , Cantarel, Brandi L. , Lamendella, Regina , Darzi, Youssef , Mongodin, Emmanuel F. , Pan, Chongle , Shah, Manesh , Halfvarson, Jonas , Tysk, Curt , Henrissat, Bernard , Raes, Jeroen , Verberkmoes, Nathan C. , Fraser, Claire M. , Hettich, Robert L. and Jansson, Janet K.
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
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More information
Scope and Contents
Contents
Crohn's disease (CD) is an inflammatory bowel disease of complex etiology, although dysbiosis of the gut microbiota has been implicated in chronic immune-mediated inflammation associated with CD. Here we combined shotgun metagenomic and metaproteomic approaches to identify potential functional signatures of CD in stool samples from six twin pairs t...
Alternative Titles
Full title
Integrated Metagenomics/Metaproteomics Reveals Human Host-Microbiota Signatures of Crohn's Disease
Authors, Artists and Contributors
Author / Creator
Erickson, Alison R.
Cantarel, Brandi L.
Lamendella, Regina
Darzi, Youssef
Mongodin, Emmanuel F.
Pan, Chongle
Shah, Manesh
Halfvarson, Jonas
Tysk, Curt
Henrissat, Bernard
Raes, Jeroen
Verberkmoes, Nathan C.
Fraser, Claire M.
Hettich, Robert L.
Jansson, Janet K.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1350901848
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1350901848
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0049138
