MEPE-Derived ASARM Peptide Inhibits Odontogenic Differentiation of Dental Pulp Stem Cells and Impair...
MEPE-Derived ASARM Peptide Inhibits Odontogenic Differentiation of Dental Pulp Stem Cells and Impairs Mineralization in Tooth Models of X-Linked Hypophosphatemia
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Author / Creator
Salmon, Benjamin , Bardet, Claire , Khaddam, Mayssam , Naji, Jiar , Coyac, Benjamin R. , Baroukh, Brigitte , Letourneur, Franck , Lesieur, Julie , Decup, Franck , Le Denmat, Dominique , Nicoletti, Antonino , Poliard, Anne , Rowe, Peter S. , Huet, Eric , Vital, Sibylle Opsahl , Linglart, Agnès , McKee, Marc D. and Chaussain, Catherine
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Mutations in PHEX (phosphate-regulating gene with homologies to endopeptidases on the X-chromosome) cause X-linked familial hypophosphatemic rickets (XLH), a disorder having severe bone and tooth dentin mineralization defects. The absence of functional PHEX leads to abnormal accumulation of ASARM (acidic serine- and aspartate-rich motif) peptide -...
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Full title
MEPE-Derived ASARM Peptide Inhibits Odontogenic Differentiation of Dental Pulp Stem Cells and Impairs Mineralization in Tooth Models of X-Linked Hypophosphatemia
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Record Identifier
TN_cdi_plos_journals_1351357890
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1351357890
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0056749
