Comparative In Vitro and In Silico Analyses of Variants in Splicing Regions of BRCA1 and BRCA2 Genes...
Comparative In Vitro and In Silico Analyses of Variants in Splicing Regions of BRCA1 and BRCA2 Genes and Characterization of Novel Pathogenic Mutations
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Several unclassified variants (UVs) have been identified in splicing regions of disease-associated genes and their characterization as pathogenic mutations or benign polymorphisms is crucial for the understanding of their role in disease development. In this study, 24 UVs located at BRCA1 and BRCA2 splice sites were characterized by transcripts ana...
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Comparative In Vitro and In Silico Analyses of Variants in Splicing Regions of BRCA1 and BRCA2 Genes and Characterization of Novel Pathogenic Mutations
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TN_cdi_plos_journals_1351358133
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1351358133
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0057173
