VPO1 mediates ApoE oxidation and impairs the clearance of plasma lipids
VPO1 mediates ApoE oxidation and impairs the clearance of plasma lipids
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United States: Public Library of Science
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English
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United States: Public Library of Science
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ApoE is an abundant component of chylomicron, VLDL, IDL, and HDL. It binds to multiple types of lipids and is implicated in cholesterol and triglyceride homeostasis. Oxidation of ApoE plays a crucial role in the genesis of atherosclerosis. It is proposed that heme-containing peroxidases (hPx) are major mediators of lipoprotein oxidization. Vascular...
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VPO1 mediates ApoE oxidation and impairs the clearance of plasma lipids
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TN_cdi_plos_journals_1351902117
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1351902117
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0057571