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VPO1 mediates ApoE oxidation and impairs the clearance of plasma lipids

VPO1 mediates ApoE oxidation and impairs the clearance of plasma lipids

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1351902117

VPO1 mediates ApoE oxidation and impairs the clearance of plasma lipids

About this item

Full title

VPO1 mediates ApoE oxidation and impairs the clearance of plasma lipids

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-02, Vol.8 (2), p.e57571

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

ApoE is an abundant component of chylomicron, VLDL, IDL, and HDL. It binds to multiple types of lipids and is implicated in cholesterol and triglyceride homeostasis. Oxidation of ApoE plays a crucial role in the genesis of atherosclerosis. It is proposed that heme-containing peroxidases (hPx) are major mediators of lipoprotein oxidization. Vascular...

Alternative Titles

Full title

VPO1 mediates ApoE oxidation and impairs the clearance of plasma lipids

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1351902117

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1351902117

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0057571

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