Identification of cisplatin-binding proteins using agarose conjugates of platinum compounds
Identification of cisplatin-binding proteins using agarose conjugates of platinum compounds
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Cisplatin is widely used as an antineoplastic drug, but its ototoxic and nephrotoxic side-effects, as well as the inherent or acquired resistance of some cancers to cisplatin, remain significant clinical problems. Cisplatin's selectivity in killing rapidly proliferating cancer cells is largely dependent on covalent binding to DNA via cisplatin's ch...
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Full title
Identification of cisplatin-binding proteins using agarose conjugates of platinum compounds
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TN_cdi_plos_journals_1362916854
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1362916854
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0066220
