Osteoprotegerin inhibits aortic valve calcification and preserves valve function in hypercholesterol...
Osteoprotegerin inhibits aortic valve calcification and preserves valve function in hypercholesterolemic mice
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
There are no rigorously confirmed effective medical therapies for calcific aortic stenosis. Hypercholesterolemic Ldlr (-/-) Apob (100/100) mice develop calcific aortic stenosis and valvular cardiomyopathy in old age. Osteoprotegerin (OPG) modulates calcification in bone and blood vessels, but its effect on valve calcification and valve function is...
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Full title
Osteoprotegerin inhibits aortic valve calcification and preserves valve function in hypercholesterolemic mice
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TN_cdi_plos_journals_1365653312
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1365653312
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0065201
