Promoter DNA methylation pattern identifies prognostic subgroups in childhood T-cell acute lymphobla...
Promoter DNA methylation pattern identifies prognostic subgroups in childhood T-cell acute lymphoblastic leukemia
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Treatment of pediatric T-cell acute lymphoblastic leukemia (T-ALL) has improved, but there is a considerable fraction of patients experiencing a poor outcome. There is a need for better prognostic markers and aberrant DNA methylation is a candidate in other malignancies, but its potential prognostic significance in T-ALL is hitherto undecided.
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Full title
Promoter DNA methylation pattern identifies prognostic subgroups in childhood T-cell acute lymphoblastic leukemia
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TN_cdi_plos_journals_1365653516
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1365653516
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0065373