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Promoter DNA methylation pattern identifies prognostic subgroups in childhood T-cell acute lymphobla...

Promoter DNA methylation pattern identifies prognostic subgroups in childhood T-cell acute lymphobla...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1365653516

Promoter DNA methylation pattern identifies prognostic subgroups in childhood T-cell acute lymphoblastic leukemia

About this item

Full title

Promoter DNA methylation pattern identifies prognostic subgroups in childhood T-cell acute lymphoblastic leukemia

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-06, Vol.8 (6), p.e65373-e65373

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Treatment of pediatric T-cell acute lymphoblastic leukemia (T-ALL) has improved, but there is a considerable fraction of patients experiencing a poor outcome. There is a need for better prognostic markers and aberrant DNA methylation is a candidate in other malignancies, but its potential prognostic significance in T-ALL is hitherto undecided.
G...

Alternative Titles

Full title

Promoter DNA methylation pattern identifies prognostic subgroups in childhood T-cell acute lymphoblastic leukemia

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1365653516

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1365653516

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0065373