Interaction between NBS1 and the mTOR/Rictor/SIN1 Complex through Specific Domains
Interaction between NBS1 and the mTOR/Rictor/SIN1 Complex through Specific Domains
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Nijmegen breakage syndrome (NBS) is a chromosomal-instability syndrome. The NBS gene product, NBS1 (p95 or nibrin), is a part of the Mre11-Rad50-NBS1 complex. SIN1 is a component of the mTOR/Rictor/SIN1 complex mediating the activation of Akt. Here we show that NBS1 interacted with mTOR, Rictor, and SIN1. The specific domains of mTOR, Rictor, or SI...
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Full title
Interaction between NBS1 and the mTOR/Rictor/SIN1 Complex through Specific Domains
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TN_cdi_plos_journals_1365653722
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1365653722
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0065586
