Combined 5-FU and ChoKα inhibitors as a new alternative therapy of colorectal cancer: evidence in hu...
Combined 5-FU and ChoKα inhibitors as a new alternative therapy of colorectal cancer: evidence in human tumor-derived cell lines and mouse xenografts
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Colorectal cancer (CRC) is the third major cause of cancer related deaths in the world. 5-fluorouracil (5-FU) is widely used for the treatment of colorectal cancer but as a single-agent renders low response rates. Choline kinase alpha (ChoKα), an enzyme that plays a role in cell proliferation and transformation, has been reported overexpressed in m...
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Combined 5-FU and ChoKα inhibitors as a new alternative therapy of colorectal cancer: evidence in human tumor-derived cell lines and mouse xenografts
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TN_cdi_plos_journals_1366366783
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1366366783
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0064961