Identification of pVHL as a novel substrate for Aurora-A in clear cell renal cell carcinoma (ccRCC)
Identification of pVHL as a novel substrate for Aurora-A in clear cell renal cell carcinoma (ccRCC)
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Clear cell renal cell carcinoma (ccRCC) is the most common histological subtype of kidney cancer and is often characterized by mutations or deletions of the Von Hippel Lindau (VHL) tumour suppressor gene. Aurora gene family members are implicated in proper mitotic progression and spindle checkpoint function and play a crucial role in cancer progres...
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Full title
Identification of pVHL as a novel substrate for Aurora-A in clear cell renal cell carcinoma (ccRCC)
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TN_cdi_plos_journals_1367545566
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1367545566
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0067071
