IL-21 Restricts Virus-driven Treg Cell Expansion in Chronic LCMV Infection
IL-21 Restricts Virus-driven Treg Cell Expansion in Chronic LCMV Infection
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Foxp3+ regulatory T (Treg) cells are essential for the maintenance of immune homeostasis and tolerance. During viral infections, Treg cells can limit the immunopathology resulting from excessive inflammation, yet potentially inhibit effective antiviral T cell responses and promote virus persistence. We report here that the fast-replicating LCMV str...
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Full title
IL-21 Restricts Virus-driven Treg Cell Expansion in Chronic LCMV Infection
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TN_cdi_plos_journals_1368604542
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1368604542
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1003362
